Shrinking and discoloration of bitter gourd leaves are the hallmarks of Kikudi disease. It is a disease caused by a virus which is spread from one plant to another by white fly. For its control, insecticides like Viroline, 40 ml or Tatamida, 15 ml. + Manik, 8-10 g. Spray it by dissolving it in every 15 liters of water. After 4-5 days, spray calcium like Aquacal 30-40 ml in 15 liters of water.